Product Description
| Cat Number | T60079 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | GNE-064 is a selective, orally active and highly soluble inhibitor of SMARCA4, SMARCA2 and PBRM1 bromodomains 5. GNE-064 inhibits SMARCA4 with an IC50 of 0.035 μM and inhibits SMARCA2 with an EC50 of 0.10 μM. GNE-064 possess Kds with 0.01, 0.016, 0.018 and 0.049 μM for SMARCA4, SMARCA2, PBRM1 bromodomains 5 and PBRM1 bromodomains 2, repectively. GNE-064 can be used as a chemical probe for the research of drug synthesis. |
| Molecular Weight | 327.38 |
| Purity | 0.9981 |
| Formula | C17H21N5O2 |
| Smiles | C[C@@H]1CN(CCN1C(C)=O)c1cc(nnc1N)-c1ccccc1O |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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