Product Description
| Cat Number | T60150 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | (1S,2R)-Alicapistat ((1S,2R)-ABT-957) is a highly efficient, orally active compound that selectively inhibits human calpains 1 and 2, showing promise for Alzheimer's disease (AD) therapy [1]. It effectively addresses the metabolic liability associated with carbonyl reduction and demonstrates potent inhibition of calpain 1 with an IC50 value of 395 nM [2]. |
| Molecular Weight | 433.5 |
| Purity | 0.9805 |
| Formula | C25H27N3O4 |
| Smiles | O=C(N[C@@H](Cc1ccccc1)C(=O)C(=O)NC1CC1)[C@H]1CCC(=O)N1Cc1ccccc1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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