Product Description
| Cat Number | T60159 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | PBRM1-BD2-IN-5 is a potent inhibitor of the PBRM1 Bromodomain, with dissociation constant (Kd) values of 1.5 μM and 3.9 μM for PBRM1-BD2 and PBRM1-BD5 respectively, and an inhibitory concentration 50 (IC50) value of 0.26 μM for PBRM1-BD2. This compound effectively diminishes the interaction between full-length PBRM1 and acetylated histone peptide within the PBAF complex in cell lysates, making it a promising candidate for anticancer research. |
| Molecular Weight | 272.73 |
| Purity | 0.9955 |
| Formula | C15H13ClN2O |
| Smiles | O=C1C=2C(NC(N1)C3=CC(C)=CC=C3)=CC=CC2Cl |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
Share Item: