Product Description
| Cat Number | T60187 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | RP-6685, a highly potent and selective inhibitor of DNA polymerase theta (Polθ), manifests remarkable oral activity. With an IC 50 value of 5.8 nM in the PicoGreen assay, RP-6685 effectively hinders the enzymatic activity of Polθ. In addition, it demonstrates significant antitumor efficacy as observed in a mouse tumor xenograft model [1]. |
| Molecular Weight | 497.37 |
| Purity | 0.9834 |
| Formula | C22H14F7N5O |
| Smiles | Nc1ccc(nn1)C#CCN(C(=O)Cc1ncc(cc1C(F)(F)F)C(F)(F)F)c1ccc(F)cc1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
Share Item: