Product Description
| Cat Number | T6023 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction (Ki=90 nM) and activates p53. Nutlin-3a binds preferentially to the p53-binding pocket of MDM2, leading to stabilization of p53 and activation of the p53 pathway. Nutlin-3a has antitumor activity. |
| Molecular Weight | 581.49 |
| Purity | 0.9971 |
| Formula | C30H30Cl2N4O4 |
| Smiles | COc1ccc(C2=N[C@H]([C@H](N2C(=O)N2CCNC(=O)C2)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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