Product Description
| Cat Number | T60336 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | CCR4 antagonist 3-1 is a less active chemokine receptor 4 (CCR4) antagonist that inhibits [125I]TARC (thymus and activation-regulated chemokine) with an IC50 value of 1.7 μM. CCR4 antagonist 3-1 inhibits the binding of radiolabeled [125I]TARC and macrophage-derived chemokine ( MDC) to CEM cell surface and inhibits TARC-mediated CEM cell migration in vitro with an IC50 value of 6.4 μM. CCR4 antagonist 3 inhibited the binding of radiolabeled [125I]TARC and macrophage-derived chemokine (MDC) to the CCR4 receptor on the surface of CEM cells and inhibited TARC-mediated migration of CEM cells in vitro with an IC50 value of 6.4 μM. |
| Molecular Weight | 240.32 |
| Purity | 0.9953 |
| Formula | C14H12N2S |
| Smiles | N(C=1C2=C(C=CC1)C=CC=C2)C3=NC(C)=CS3 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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