Product Description
| Cat Number | T6070 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | ON-01910 is a non-ATP-competitive PLK1 inhibitor(IC50 of 9 nM, in a cell-free assay). It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidative stress signals. Rigosertib induces apoptosis in various cancer cells.It is a synthetic benzyl styryl sulfone analogue with potential antineoplastic activity. |
| Molecular Weight | 473.47 |
| Purity | 0.9911 |
| Formula | C21H24NNaO8S |
| Smiles | [Na+].COc1cc(OC)c(C=CS(=O)(=O)Cc2ccc(OC)c(NCC([O-])=O)c2)c(OC)c1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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