Product Description
| Cat Number | T61025 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | GSK-1482160 is a CNS-penetrant negative allosteric modulator of P2X7 receptor with oral activity. The P2X7 receptor is involved in the production of pro-inflammatory cytokines by central and peripheral immune cells, so GSK-1482160 has the potential to study inflammatory diseases. GSK-1482160 shows excellent in vitro potency (in functional and electrophysiological assays at recombinant and naive P2X7 receptors across multiple species including humans) and cross-target selectivity. |
| Molecular Weight | 334.72 |
| Purity | 0.9987 |
| Formula | C14H14ClF3N2O2 |
| Smiles | CN1[C@@H](CCC1=O)C(=O)NCc1cccc(c1Cl)C(F)(F)F |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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