Product Description
| Cat Number | T6264 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Bosentan (Benzenesulfonamide) is a sulfonamide-derived, competitive and specific endothelin receptor antagonist with a slightly higher affinity for the endothelin A receptor than endothelin B receptor. Bosentan blocks the action of endothelin 1, an extremely potent endogenous vasoconstrictor and bronchoconstrictor, by binding to endothelin A and endothelin B receptors in the endothelium and vascular smooth muscle. Bosentan decreases both pulmonary and systemic vascular resistance and is particularly used in the treatment of pulmonary arterial hypertension. |
| Molecular Weight | 551.614 |
| Purity | 0.9984 |
| Formula | C27H29N5O6S |
| Smiles | COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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