Product Description
| Cat Number | T62826 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | HOIPIN-8 is a potent inhibitor of the linear ubiquitin chain assembly complex (LUBAC) with an IC50 of 11 nM. As a derivative of HOIPIN-1, it exhibits 255-fold greater inhibition of both petit-LUBAC and TNF-α-mediated NF-κB activation compared to HOIPIN-1. HOIPIN-8 is a promising tool to explore cellular functions of LUBAC. |
| Molecular Weight | 456.38 |
| Purity | 0.9734 |
| Formula | C23H15F2N4NaO3 |
| Smiles | O=C(C1=CC=C(C2=CN(C)N=C2)C=C1/C=C/C(C3=C(C=C(C4=CNN=C4)C=C3F)F)=O)[O-].[Na+] |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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