Product Description
| Cat Number | T63516 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | NRX-252114 (NRX252114) induces degradation of mutant β-catenin NRX-252114 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP, and is able to enhance the binding of pSer33/S37A β-catenin to β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. Kd is 0.4 nM. |
| Molecular Weight | 510.32 |
| Purity | 0.9826 |
| Formula | C22H12Cl2F3N3O2S |
| Smiles | S(C1=C(C(=O)N2CC=3C(C2)=CC=CC3C#N)C(=O)NC(C(F)(F)F)=C1)C4=C(Cl)C=CC=C4Cl |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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