Product Description
| Cat Number | T6517 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity. c-Met/VEGFR kinase inhibitor E7050 binds to and inhibits the activities of both c-Met and VEGFR-2, which may inhibit tumor cell growth and survival of tumor cells that overexpress these receptor tyrosine kinases. c-Met and VEGFR-2 are upregulated in a variety of tumor cell types and play important roles in tumor cell growth, migration and angiogenesis. |
| Molecular Weight | 633.69 |
| Purity | 0.9868 |
| Formula | C33H37F2N7O4 |
| Smiles | CN1CCN(CC1)C1CCN(CC1)C(=O)Nc1cc(Oc2ccc(NC(=O)C3(CC3)C(=O)Nc3ccc(F)cc3)c(F)c2)ccn1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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