Product Description
| Cat Number | T6763 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1. |
| Molecular Weight | 561.71 |
| Purity | 0.9956 |
| Formula | C32H43N5O4 |
| Smiles | CN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1)C(=O)CC(C)C |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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