Product Description
| Cat Number | T67951 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | JB061 is a nonmuscle myosin inhibitor, demonstrating selective inhibitory activity with IC50 values of 4.4 μM (Cardiac muscle myosin), 9.1 μM (Skeletal muscle myosin), and >100 μM (Smooth muscle myosin II). It exhibits limited efficacy in reducing ATPase activity, with an IC50 exceeding 200 μM. Furthermore, JB061 displays cytotoxic effects on COS-7 cells, evidenced by an IC50 value of 39 μM. |
| Molecular Weight | 323.34 |
| Purity | 0.9876 |
| Formula | C19H17NO4 |
| Smiles | COc1cccc(C\N=C(/C)c2c(O)c3ccccc3oc2=O)c1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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