Product Description
| Cat Number | T68405 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free base selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in the stimulation of cellular proliferation, oncogenic transformation, and suppression of apoptosis. |
| Molecular Weight | 515.63 |
| Purity | 0.9911 |
| Formula | C28H29N5O3S |
| Smiles | C(=C/C1=C(NC(=O)C=2SC=CC2C)C=C(CN3CCN(C(CO)=O)CC3)C=C1)\C=4C=5C(NN4)=CC=CC5 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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