Product Description
| Cat Number | T68599 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Orphenadrine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that inhibits clonal HERG channels in a concentration-dependent manner, producing an IC of 0.85 μM in HEK cells.Orphenadrine is an antagonist of central and peripheral muscarinic receptors. Attenuation is blocked by mutations in pore residues Y652 or F656. Orphenadrine has antispasmodic, analgesic, and anticholinergic activity and protects against glutamatergic neurotoxicity in vitro and in vivo.Orphenadrine has inhibitory effects on sodium channels and can be used in the treatment of Parkinson's disease. |
| Molecular Weight | 269.38 |
| Purity | 0.9938 |
| Formula | C18H23NO |
| Smiles | C(OCCN(C)C)(C1=C(C)C=CC=C1)C2=CC=CC=C2 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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