Product Description
| Cat Number | T6904 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | (E)-Necrosulfonamide ((E)-Necrosulfonamide) is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during necrosis. Prevents MLKL-RIP1-RIP3 necrosome complex from interacting with downstream necrosis effectors. Binds and inhibits gasdermin D. Inhibits pyroptosis. |
| Molecular Weight | 461.47 |
| Purity | 0.9949 |
| Formula | C18H15N5O6S2 |
| Smiles | COc1nccnc1NS(=O)(=O)c1ccc(NC(=O)\C=C\c2ccc(s2)[N+]([O-])=O)cc1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |

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