Product Description
| Cat Number | T6S0735 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | 1. Flavokawain B (Flavokavain B) has potent anti-inflammatory activity, can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. 2. Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-κB and MAPK signaling pathways. 3. Flavokawain B induces apoptosis, has the potential usefulness of FKB for prevention and treatment of hormone-refractory prostate cancer in an adjuvant setting. 4. Flavokawain B acts through ROS generation and GADD153 up-regulation to regulate the expression of Bcl-2 family members, thereby inducing mitochondrial dysfunction and apoptosis in HCT116 cells. |
| Molecular Weight | 284.31 |
| Purity | 1 |
| Formula | C17H16O4 |
| Smiles | COC1=CC(OC)=C(C(=O)\C=C\C2=CC=CC=C2)C(O)=C1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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