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Recombinant Human Triggering receptor expressed on myeloid cells 2 (TREM2) ,partial
Cat No:RPC28752 | Brand:Biomatik
Description
| Category | Recombinant Protein |
|---|---|
| Source | E.coli |
| Source Buffer | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
| Expression Region | 19-174aa |
| Purity | Greater than 85% as determined by SDS-PAGE. |
| Molecular Mass Weight | 52.6 kDa |
| Endotoxin Level | Not Tested |
| Restriction | For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals. |
| Relevance | Forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849) . Acts as a receptor for amyloid-beta protein 42, a cleavage product of the amyloid-beta precursor protein APP, and mediates its uptake and degradation by microglia (PubMed:27477018, PubMed:29518356) . Binding to amyloid-beta 42 mediates microglial activation, prol |
| Alternative name | Triggering receptor expressed on myeloid cells 2 (TREM-2) (Triggering receptor expressed on monocytes 2) |
| Storage | Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles. |
| Uniprot Number | Q9NZC2 |
| Tag Information | N-terminal 10xHis-GST-tagged and C-terminal Myc-tagged |
| Species | Homo sapiens (Human) |
| Gene Name | TREM2 |
| Research Area | Immunology |
| Note | The product is for research use only. |
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