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OP-145

SKU: BTL-IB-P-00248 | Brand: Isca Biochemical
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Product Description
Cat Number AM-360
Category Peptide
Pack Size 1 mg
Description Antimicrobial peptide derived from LL-37
Modification N terminal acetyl, C terminal amide
Purity >95% by hplc
Biomarker Target Antibacterials
Sequence Three Letter Code Ac-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Glu-Arg-Ile-Lys-Arg-Phe-Leu-Arg-Glu-Leu-Val-Arg-Pro-Leu-Arg-NH2
Molecular Formula C142H246N46O31
Sl Sequence Ac-IGKEFKRIVERIKRFLRELVRPLR-NH2
Solubility Soluble in water
Appearance Freeze dried solid
Storage Store dry, frozen and in the dark
References Nell et al (2006) Development of novel LL-37 derived antimicrobial peptides with LPS and LTA neutralizing and antimicrobial activities for therapeutic application. Peptides 27(4):649  PMID: 16274847Malanovic et al (2015) Phospholipid-driven differences determine the action of the synthetic antimicrobial peptide OP-145 on Gram-positive bacterial and mammalian membrane model systems. Biochim Biophys Acta. 1848(10 Pt A) 2437 PMID: 26210299Ming and Huang (20217) The Antibacterial Effects of Antimicrobial Peptides OP-145 against Clinically Isolated Multi-Resistant Strains. Jpn J Infect Dis. 70(6) 601 PMID: 28890511Cheng et al (2022) The antimicrobial effects of PLGA microspheres containing the antimicrobial peptide OP-145 on clinically isolated pathogens in bone infections. Sci Rep. 12(1) 14541 PMID: 36008534
Related areasAll antimicrobial peptides >All immunology research categories >
Note The product is for research use only
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