Product Description
| Cat Number | CG-060 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | Selective amylin antagonist |
| Modification | N-terminal Ac, C-terminal amide |
| Purity | >95% by hplc |
| Biomarker Target | Calcitonin and related receptors |
| Sequence Three Letter Code | Ac-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Asn-Thr-Tyr-NH2 |
| Molecular Formula | C127H205N37O40 |
| Sl Sequence | Ac-VLGKLSQELHKLQTYPRTNTGSNTY-NH2 |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| References |
Rushing (2001) Inhibition of central amylin signaling increases food intake and body adiposity in rats. Endocrinolog 142(11) 5035 PMID: 11606473Mollet (2004) Infusion of the amylin antagonist AC 187 into the area postrema increases food intake in rats. Physiol Behav. 81(1) 149 PMID: 15059694Gedulin et al (2006) Role of endogenous amylin in glucagon secretion and gastric emptying in rats demonstrated with the selective antagonist, AC187. Regul.Pept. 137 121 PMID: 16914214 Related areasAll peptides >All calcitonin and related receptors >All appetite regulation research categories > |
| Note | The product is for research use only |
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