Product Description
| Cat Number | CV-040 |
|---|---|
| Category | Peptide |
| Pack Size | 10 mg |
| Description | Human immunodeficiency virus (HIV)-1 protease inhibitor |
| Purity | >98% by hplc; NMR conforms to structure |
| Biomarker Target | Kinases,Other proteases,Antivirals |
| Sequence Three Letter Code | (3S,4aS,8aS)-N-(1,1-Dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy- 2-methylbenzoyl)amino]-4-(phenylthio)butyl]-3-isoquinolinecarboxamide methanesulfonate |
| Molecular Formula | C32H45N3O4S. CH3SO3H |
| Sl Sequence | (3S,4aS,8aS)-N-(1,1-Dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy- 2-methylbenzoyl)amino]-4-(phenylthio)butyl]-3-isoquinolinecarboxamide methanesulfonate |
| Solubility | Soluble in DMSO to 70mg/ml |
| Appearance | White powder |
| Storage | Store dessicated, frozen and in the dark |
| References |
Patick et al (1996) Antiviral and resistance studies of AG1343, an orally bioavailable inhibitor of human immunodeficiency virus protease. Antimicrob.Agents Chemother. 40 29 PMID: 8787874Gills et al (2007) Nelfinavir, a lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy and apoptosis in vitro and in vivo. Clin.Cancer Res. 13 5183 PMID: 17785575Ko et al (2020) Screening of FDA-approved drugs using a MERS-CoV clinical isolate from South Korea identifies potential therapeutic options for COVID-19. BioRxiv 2020.02.25.965582 PMID: 33918958 Related areas_x000D_ All small molecules >All antiviral agents >All cancer research categories > |
| Note | The product is for research use only |
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