Product Description
| Cat Number | CV-070 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | FRET substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro) |
| Modification | N terminal 7-methoxycoumarin (Mca), C terminal amide, lysine 9 has 2,4-dinitrophenyl (Dnp) attached |
| Purity | >95% by HPLC |
| Biomarker Target | Serine proteases,Antivirals |
| Sequence Three Letter Code | Mca-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg-Lys(Dnp)-Lys-NH2 |
| Molecular Formula | C69H99N19O20 |
| Sl Sequence | Mca-AVLQSGFRK(Dnp)K-NH2 |
| Solubility | Soluble as a stock solution in DMSO |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| References |
Yang et al (2005) Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases. PLoS Biol. 3(10) e324 PMID: 16128623Zhao et al (2008). Structure of the Main Protease from a Global Infectious Human Coronavirus, HCoV-HKU1. J. Virol. 82(17) 8647 PMID: 18562531Bahun et al (2021) Inhibition of the SARS-CoV-2 3CLpro main protease by plant polyphenols,_x000D_
Food Chemistry 131594 https://doi.org/10.1016/j.foodchem.2021.131594. Related areasAll serine protease modulators >All fluorescent labelled peptides >All substrate peptides >All antivirals > |
| Note | The product is for research use only |
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