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rytvela

SKU: BTL-IB-P-00328 | Brand: Isca Biochemical

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Product Description

Cat Number	CY-030
Category	Peptide
Pack Size	1 mg
Description	IL-1 receptor allosteric antagonist
Modification	All amino acids are D isomers
Purity	>95% by hplc
Biomarker Target	Cytokine receptors
Sequence Three Letter Code	H-(D)Arg-(D)Tyr-(D)Thr-(D)Val-(D)Glu-(D)Leu-(D)Ala-OH
Molecular Formula	C38H62N10O12
Sl Sequence	rytvela
Solubility	Soluble in water
Appearance	Freeze dried solid
Storage	Store dry, frozen and in the dark
References	Quiniou et al (2008) Development of a novel noncompetitive antagonist of IL-1 receptor. J Immunol. 180(10) 6977 PMID: 18453620Dabouz (2020) An allosteric interleukin-1 receptor modulator mitigates inflammation and photoreceptor toxicity in a model of retinal degeneration. J Neuroinflammation. 17(1) 359 PMID: 33246504Takahashi (2021) Direct administration of the non-competitive interleukin-1 receptor antagonist rytvela transiently reduced intrauterine inflammation in an extremely preterm sheep model of chorioamnionitis. PLoS One 16(9) e0257847 PMID: 34559862 Related areas All peptides >All cytokine receptor modulators >All immunology research areas >
Note	The product is for research use only

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