Product Description
| Cat Number | DA-020 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | D1-D2 heteromer antagonist |
| Modification | None |
| Purity | >95% by hplc |
| Biomarker Target | Dopamine receptors |
| Sequence Three Letter Code | H-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Gln-Gly-Ser-Ser-Glu-Asp-Leu-Lys-Lys-Glu-Glu-Ala-Ala-Gly-Ile-Ala-Arg-Pro-Leu-OH |
| Molecular Formula | C144H257N57O43 |
| Sl Sequence | GRKKRRQRRRPQGSSEDLKKEEAAGIARPL |
| Solubility | Soluble in saline |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| References |
Hasbi et al (2014) A peptide targeting an interaction interface disrupts the dopamine D1-D2 receptor heteromer to block signaling and function in vitro and in vivo: effective selective antagonism. FASEB J. 11 4806 PMID: 25063849Shen et al (2015) The dopamine D1-D2 receptor heteromer exerts a tonic inhibitory effect on the expression of amphetamine-induced locomotor sensitization. Pharmacol Biochem Behav. 128 33 PMID: 25444866Andrianarivelo et al (2019) Modulation and functions of dopamine receptor heteromers in drugs of abuse-induced adaptations. Neuropharmacology 152 42 PMID: 30529032 Related areasAll cell penetrating peptides >All dopamine receptor modulators >All neuroscience research categories > |
| Note | The product is for research use only |
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