Product Description
| Cat Number | KC-010 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | Inward rectifier K+ channel blocker |
| Modification | Disulphide bridges between C-3 and C14 and C-5 and C-18, Lys-21 is a C-terminal amide |
| Purity | >95% by hplc |
| Biomarker Target | Potassium channels |
| Sequence Three Letter Code | H-Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Gln-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2: disulphide bridges between Cys-3 and Cys-14 and Cys-5 and Cys-18 |
| Molecular Formula | C106H175N35O24S4 |
| Sl Sequence | ALCNCNRIIIPHQCWKKCGKK-NH2 |
| Solubility | Soluble to 2 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| References |
Jin and Lu (1999) Synthesis of a stable form of tertiapin: a high-affinity inhibitor for inward-rectifier K+ channels. Biochemistry 38 14286 PMID: 10572003Jin et al (1999) Mechanisms of inward-rectifier K+ channel inhibition by tertiapin-Q. Biochemistry 38 14294 PMID: 10572004Kanjhan et al (2005) Tertiapin-Q blocks recombinant and native large conductance K+ channels in a use-dependent manner. J Pharmacol Exp Ther. 314(3) 1353 PMID: 15947038 Related areas_x000D_ All peptides >All potassium channel modulators >All cardiovascular research areas >All neuroscience research categories > |
| Note | The product is for research use only |
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