Product Description
| Cat Number | KC-020 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | Selective IKACh blocker |
| Modification | Disulphide bridges between C-3 and C14 and C-5 and C-18, Lys-21 is a C-terminal amide |
| Purity | >95% by hplc |
| Biomarker Target | Potassium channels |
| Sequence Three Letter Code | H-Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Met-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2; disulphide bridges between Cys-3 and Cys-14 and Cys-5 and Cys-18 |
| Molecular Formula | C106H176N34O23S5 |
| Sl Sequence | ALCNCNRIIIPHMCWKKCGKK-NH2 |
| Solubility | Soluble in water to 1 mg/m |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark. Protect from air. |
| References |
Gauldie et al (1976) The peptide components of bee venom. Eur J Biochem. 61(2):369 PMID: 1248464Hashimoto et al (2006) Tertiapin, a selective IKACh blocker, terminates atrial fibrillation with selective atrial effective refractory period prolongation. Pharmacol Res. 54(2) 136 PMID: 16725344Patel et al (2020) Structural Determinants Mediating Tertiapin Block of Neuronal Kir3.2 Channels. Biochemistry 59(7) 836 PMID: 31990535 Related areas_x000D_ All peptides >All potassium channel modulators >All cardiovascular research categories > |
| Note | The product is for research use only |
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