Product Description
| Cat Number | KC-030 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | Selective Kir1.1 blocker |
| Modification | Disulfide bridges between cysteines 3 - 14, and 5 - 18, C-terminal amide |
| Purity | >95% by hplc |
| Biomarker Target | Potassium channels |
| Sequence Three Letter Code | H-Ala-Leu-Cys*-Asn-Cys*-Asn-Arg-Ile-Ile-Ile-Pro-Leu-Gln-Cys*-Trp-Lys-Lys-Cys*-Gly-Lys-Lys-NH2; disulfide bridges between cysteines 3 - 14 and 5 - 18 |
| Molecular Formula | C106H179N33O24S4 |
| Sl Sequence | ALCNCNRIIIPLQCWKKCGKK-NH2 |
| Solubility | Soluble to 2 mg/ml in 20% acetonitrile / water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| References |
Ramu et al (2008) Engineered specific and high-affinity inhibitor for a subtype of inward-rectifier K+ channels. Proc.Natl.Acad.Sci.USA 105 10774 PMID: 18669667Estrada and Kaufman (2018) µ-Opioid receptors inhibit the exercise pressor reflex by closing N-type calcium channels but not by opening GIRK channels in rats. Am J Physiol Regul Integr Comp Physiol. 314(5) R693 PMID: 29341826Johansson and Hesslow (2020) Kir3 channel blockade in the cerebellar cortex suppresses performance of classically conditioned Purkinje cell responses. Sci Rep 10 15654 PMID: 32973240Pubchem entry for tertiapin LQ Related areas_x000D_ All peptides >All potassium channel modulators >All neuroscience research categories > |
| Note | The product is for research use only |
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