Product Description
| Cat Number | KS-180 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | Selective inhibitor of myosin light chain kinase |
| Modification | C-terminal amide |
| Purity | >95% by hplc |
| Biomarker Target | Kinases |
| Sequence Three Letter Code | H-Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys-NH2 |
| Molecular Formula | C60H105N23O11 |
| Sl Sequence | RKKYKYRRK-NH2 |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| References |
Lukas et al (1999) Identification of novel classes of protein kinase inhibitors using combinatorial peptide chemistry based on functional genomics knowledge. J.Med.Chem. 42 910 PMID: 10072688Jin and Blikslager (2016) Myosin light chain kinase mediates intestinal barrier dysfunction via occludin endocytosis during anoxia/reoxygenation injury. American J. Physiology-Cell Physiology 311(6) C996 PMID: 27760753Huang et al (2020) Wogonoside alleviates colitis by improving intestinal epithelial barrier function via the MLCK/pMLC2 pathway. Phytomedicine 68 153179 PMID: 32062328Guide to Pharmacology: MLCK inhibitor peptide 18 Related areasAll peptides >All kinase modulators > |
| Note | The product is for research use only |
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