Product Description
| Cat Number | KS-220 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | Allosteric BRAF inhibitor |
| Modification | X = PEG = -NH-CH2-CH2-O-CH2-CH2-O-CH2-C=O- |
| Purity | >95% by hplc |
| Biomarker Target | Kinases |
| Sequence Three Letter Code | H-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Gln-PEG-Thr-Arg-His-Val-Asn-Ile-Leu-Leu-Phe-Met-OH |
| Molecular Formula | C128H227N51O30S |
| Sl Sequence | GRKKRRQRRRPQXTRHVNILLFM |
| Solubility | Soluble in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| References |
Gunderwala et al (2019) Development of Allosteric BRAF Peptide Inhibitors Targeting the Dimer Interface of BRAF. ACS Chem Biol. 14(7) 1471 PMID: 31243962Cope et al (2020) Analyses of the oncogenic BRAFD594G variant reveal a kinase-independent function of BRAF in activating MAPK signaling. J Biol Chem. 295(8) 2407 PMID: 31929109 Related areasAll cell penetrating peptides >All kinase modulators >All cancer research categories > |
| Note | The product is for research use only |
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