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[Ala11, D-Leu15]-Orexin B

SKU: BTL-IB-P-00427 | Brand: Isca Biochemical
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Product Description
Cat Number OX-040
Category Peptide
Pack Size 1 mg
Description Potent and selective orexin2 receptor agonist
Modification C-terminal amide
Purity >95% by hplc
Biomarker Target Orexin receptors
Sequence Three Letter Code H-Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Ala-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
Molecular Formula C189H284N54O56S
Sl Sequence RSGPPGLQGRAQRLLQASGNHAAGILTM-NH2
Solubility Soluble to 0.30 mg/ml in water
Appearance Freeze dried solid
Storage Store dry, frozen and in the dark
References Asahi et al (2003) Development of an orexin-2 receptor selective agonist, [Ala11D-Leu15]orexin-B. Bioorg.Med.Chem.Lett. 13 111 PMID: 12467628Borgland et al (2008), Orexin B/hypocretin 2 increases glutamatergic transmission to ventral tegmental area neurons. European J. Neuroscience 28 1545  PMID: 18793323Staton et al (2018) Orexin 2 receptor stimulation enhances resilience, while orexin 2 inhibition promotes susceptibility, to social stress, anxiety and depression,_x000D_ Neuropharmacology 143 79  PMID: 30240784
Related areas_x000D_ All peptides >All orexin receptor modulators >All neuroscience categories >All appetite regulation categories >
Note The product is for research use only
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