Product Description
| Cat Number | PI-030 |
|---|---|
| Category | Peptide |
| Pack Size | 5 mg |
| Description | Inhibits the chymotrypsin like activity of the 20S proteasome |
| Modification | N-terminal N-[(Phenylmethoxy)carbonyl, Leucine 3 is leucinal |
| Purity | >98% by HPLC |
| Biomarker Target | Proteasome |
| Sequence Three Letter Code | Z-Leu-Leu-Leu-CHO |
| Molecular Formula | C26H41N3O5 |
| Sl Sequence | Z-LLL-CHO |
| Solubility | Dissolves in DMSO (45 mg/mL) or ethanol (45 mg/mL) |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| References |
Banerjee and Liefshitz (2001) Potential of the proteasome inhibitor MG-132 as an anticancer agent, alone and in combination. Anticancer Res. 21 3941 PMID: 11911275Tsubuki et al (1996) Differential inhibition of calpain and proteasome activities by peptidyl aldehydes of di-Leucine and tri-Leucine. J.Biochem. 119 572 PMID: 8830056Ma et al (2020) Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease. Cell Res. 30 678 PMID: 32541865 Related areas_x000D_ All peptides >All proteasome modulators >All immunology research categories > |
| Note | The product is for research use only |
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