Product Description
| Cat Number | PI-100 |
|---|---|
| Category | Peptide |
| Pack Size | 10 mg |
| Description | Ubiquitin specific protease 7 (USP7) inhibitor |
| Purity | ‰¥98% (HPLC) |
| Biomarker Target | Deubiquitinating enzymes |
| Sequence Three Letter Code | 1-[5-[(2,3-Dichlorophenyl)thio]-4-nitro-2-thienyl]ethanone |
| Molecular Formula | C12H7Cl2NO3S2 |
| Sl Sequence | 1-[5-[(2,3-Dichlorophenyl)thio]-4-nitro-2-thienyl]ethanone |
| Solubility | Soluble to 10 mM in DMSO |
| Appearance | Off-white solid |
| Storage | Store desiccated, frozen and in the dark |
| References |
Weinstock et al (2012) Selective dual inhibitors of the cancer-related deubiquitylating proteases USP7 and USP47. J.Med.Chem. 3 789 PMID: 24900381Chauhan et al (2012) A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance. Cancer Cell 22 345 PMID: 22975377 Related areas_x000D_ All small molecules >All deubiquitinating enzyme modulators >All cancer research categories > |
| Note | The product is for research use only |
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