Product Description
| Cat Number | PI-270 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | C3 convertase inhibitor |
| Modification | C-terminal amide, disulphide bridge between cysteines 2 and 12 |
| Purity | >95% by HPLC |
| Biomarker Target | Serine proteases |
| Sequence Three Letter Code | H-Ile-*Cys-Val-Val-Gln-Asp-Trp-Gly-His-His-Arg-*Cys-Thr-NH2 (disulphide bridge between cysteines 2 and 12) |
| Molecular Formula | C66H99N23O17S2 |
| Sl Sequence | ICVVQDWGHHRCT-NH2 |
| Solubility | Soluble to 2 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| References |
Sahu et al (1996) Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library. J Immunol. 157(2) 884 PMID: 8752942Ricklin and Lambris (2008) Compstatin: a complement inhibitor on its way to clinical application. Adv Exp Med Biol. 632 273 PMID: 19025129Mastellos et al (2015) Compstatin: a C3-targeted complement inhibitor reaching its prime for bedside intervention. Eur J Clin Invest. 45(4) 423 PMID: 25678219 Related areasAll peptides >All serine protease modulators >All immunology research categories > |
| Note | The product is for research use only |
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