info@biotechnolabs.com  |   +91- 8860924629 | 7291852429

Your Cart
Product
Product Title

2 x $5566
Total:$11132.00
Back to shop
Proceed to Checkout
SVG
SVG

Search Products from 10 Million+

SVG

P110

SKU: BTL-IB-P-00255 | Brand: Isca Biochemical
Quick Enquiry
Product Description
Cat Number PP-090
Category Peptide
Pack Size 1 mg
Description Drp1 enzyme inhibitor and blocker of  Drp1/Fis1 interaction
Modification C terminal amide
Purity >95% by hplc
Biomarker Target Protein-protein interactions
Sequence Three Letter Code H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Asp-Leu-Leu-Pro-Arg-Gly-Ser-NH2
Molecular Formula C100H179N45O25
Sl Sequence YGRKKRRQRRRGGDLLPRGS-NH2
Solubility Soluble to 1 mg/ml in water
Appearance Freeze dried solid
Storage Store dry, frozen and in the dark
References Qi et al (2013) A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity. J.Cell Sci. 126 789 PMID: 23239023Joshi et al (2018) Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetic failure and cognitive decline in Alzheimer's disease. Oncotarget 9 6128 PMID: 29464060Iqbal et al (2018) A synthetic peptide rescues rat cortical neurons from anesthetic-induced cell death, perturbation of growth and synaptic assembly. Sci Rep 11 4567 PMID: 33633281Rios et al (2023) Targeting an allosteric site in dynamin-related protein 1 to inhibit Fis1-mediated mitochondrial dysfunction. Nat Commun. 14(1) 4356 PMID: 37468472
Related areasAll protein-protein interaction modulators >All cell penetrating peptides >All neuroscience research categories >
Note The product is for research use only
SVG
SVG

Subscribe to our newsletter

Drop your email address to get regular updates about discounts and offers