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Myr-tat-CBD3

SKU: BTL-IB-P-00223 | Brand: Isca Biochemical
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Product Description
Cat Number PP-180
Category Peptide
Pack Size 1 mg
Description Blocks the  CaV2.2-CRMP2 interaction
Modification Myristoyl at N terminal
Purity >95% by HPLC
Biomarker Target Protein-protein interactions,Calcium channels,Transient receptor potential (TRP) channels
Sequence Three Letter Code Myr-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Ala-Arg-Ser-Arg-Leu-Ala-Glu-Leu-Arg-Gly-Val-Pro-Arg-Gly-Leu-OH
Molecular Formula C148H269N59O33
Sl Sequence Myr-YGRKKRRQRRRARSRLAELRGVPRGL
Solubility Soluble in DMSO
Appearance Freeze dried solid
Storage Store desiccated, frozen and in the dark
References Brittain et al (2011) Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca2+ channel complex. Nature Med. 17(7) 822 PMID: 21642979Fischer et al (2014) Sustained relief of neuropathic pain by AAV-targeted expression of CBD3 peptide in rat dorsal root ganglion. Gene Ther. 21(1) 44 PMID: 24152582François-Moutal eta al (2015) A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors. Pain 156(7) 1247 PMID: 25782368
Related areasAll cell penetrating peptides >All protein-protein interaction modulators >All calcium channel modulators >All pain research categories >
Note The product is for research use only
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