Product Description
| Cat Number | PP-360 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | Disrupts the Nef-mortalin interaction, anti-metastatic |
| Modification | None |
| Purity | >95% by hplc |
| Biomarker Target | Protein-protein interactions |
| Sequence Three Letter Code | H-Val-Gly-Phe-Pro-Val-Ala-Ala-Val-Gly-Phe-Pro-Val-Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys-OH |
| Molecular Formula | C99H144N22O32 |
| Sl Sequence | VGFPVAAVGFPVDYKDDDDK |
| Solubility | Soluble in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| References |
Shelton et al (2012) Secretion modification region-derived peptide disrupts HIV-1 Nef's interaction with mortalin and blocks virus and Nef exosome release. J Virol. 86(1) 406 PMID: 22013042Huang et al (2017) Secretion modification region-derived peptide blocks exosome release and mediates cell cycle arrest in breast cancer cells. Oncotarget 8(7) 11302 PMID: 28076321Huang et al (2022) Novel secretion modification region (SMR) peptide exhibits anti-metastatic properties in human breast cancer cells. Sci Rep. 12(1) 13204 PMID: 35915218 Related areasAll peptides >All protein-protein interaction modulators >All cancer research categories > |
| Note | The product is for research use only |
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