Product Description
| Cat Number | PP-420 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | Blocks haluronan-CD44 signaling |
| Modification | C terminal amide |
| Purity | >95% by hplc |
| Biomarker Target | Protein-protein interactions |
| Sequence Three Letter Code | H-Lys-Lys-Gly-Phe-Tyr-Lys-Lys-Lys-Gln-Cys-Arg-Pro-Ser-Lys-Gly-Arg-Lys-Arg-NH2 |
| Molecular Formula | C98H172N36O21S |
| Sl Sequence | KKGFYKKKQCRPSKGRKR-NH2 |
| Solubility | Soluble in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| References |
Muterspaugh et al (2018) Interaction of Insulin-Like Growth Factor-Binding Protein 3 With Hyaluronan and Its Regulation by Humanin and CD44. Biochemistry 57(39) 5726 PMID: 30184438Price et al (2020) IGFBP-3 Blocks Hyaluronan-CD44 Signaling, Leading to Increased Acetylcholinesterase Levels in A549 Cell Media and Apoptosis in a p53-Dependent Manner. Sci Rep. 10(1) 5083 PMID: 32193421Al Khashali et al (2022) Opposing Roles of IGFBP-3 and Heparanase in Regulating A549 Lung Cancer Cell Survival. Cells 11(22) 3533 PMID: 36428962 Related areasAll peptides >All protein-protein interaction modulators >All cancer research categories > |
| Note | The product is for research use only |
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