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P140

SKU: BTL-IB-P-00257 | Brand: Isca Biochemical

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Product Description

Cat Number	PP-480
Category	Peptide
Pack Size	1 mg
Description	HSPA8/HSC70 chaperone binder
Modification	Phosphono group at serine 10
Purity	>95% by hplc
Biomarker Target	Protein-protein interactions
Sequence Three Letter Code	H-Arg-Ile-His-Met-Val-Tyr-Ser-Lys-Arg-Ser-(PO3)-Gly-Lys-Pro-Arg-Gly-Tyr-Ala-Phe-Ile-Glu-Tyr-OH
Molecular Formula	C117H181N32O32PS
Sl Sequence	RIHMVYSKRS(PO3)GKPRGYAFIEY
Solubility	Soluble in water
Appearance	Freeze dried solid
Storage	Store dry, frozen and in the dark
References	Monneaux et al (2003) T cell recognition and therapeutic effect of a phosphorylated synthetic peptide of the 70K snRNP protein administered in MR/lpr mice. Eur J Immunol. 33(2) 287 PMID: 12548559Zimmer et al (2013) Lupuzor/P140 peptide in patients with systemic lupus erythematosus: a randomised, double-blind, placebo-controlled phase IIb clinical trial. Ann Rheum Dis. 72(11) 1830 PMID: 23172751Schall et al (2022) P140 Peptide Leads to Clearance of Autoreactive Lymphocytes and Normalizes Immune Response in Lupus-Prone Mice. Front Immunol. 13 904669 PMID: 35720371 Related areas All peptides >All protein-protein interaction modulators >All regulated cell death categories >All immunology research categories >
Note	The product is for research use only

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