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P4pal10

SKU: BTL-IB-P-00262 | Brand: Isca Biochemical

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Product Description

Cat Number	PR-100
Category	Peptide
Pack Size	1 mg
Description	PAR4 antagonist
Modification	C terminal palmitoylation, N terminal amide
Purity	>95% by hplc
Biomarker Target	Protease activated receptors,Formyl peptide receptors
Sequence Three Letter Code	Pal-Ser-Gly-Arg-Arg-Tyr-Gly-His-Ala-Leu-Arg-NH2
Molecular Formula	C65H112N22O13
Sl Sequence	Pal-SGRRYGHALR-NH2
Solubility	Soluble in DMSO
Appearance	Freeze dried solid
Storage	Store dry, frozen and in the dark
References	Covic et al (2002) Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation. Nat Med. 8(10) 1161 PMID: 12357249Strande et al (2008) Inhibiting protease-activated receptor 4 limits myocardial ischemia/reperfusion injury in rat hearts by unmasking adenosine signaling. J Pharmacol Exp Ther. 324(3) 1045 PMID: 18055876Holdfeldt et al (2020) The PAR4-derived pepducin P4Pal10 lacks effect on neutrophil GPCRs that couple to Gαq for signaling but distinctly modulates function of the Gαi-coupled FPR2 and FFAR2. Biochem Pharmacol. 180 114143 PMID: 32653592 Related data All peptides >All protease activated receptor modulators >All formyl peptide receptor modulators>All cardiovascular research categories >
Note	The product is for research use only

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