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P2pal-18S

SKU: BTL-IB-P-00260 | Brand: Isca Biochemical
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Product Description
Cat Number PR-120
Category Peptide
Pack Size 1 mg
Description PAR2 antagonist
Modification N terminal palmitoyl, C terminal amide
Purity >95% BPLC
Biomarker Target Protease activated receptors
Sequence Three Letter Code Palmitoyl-Arg-Ser-Ser-Ala-Met-Asp-Glu-Asn-Ser-Glu-Lys-Lys-Arg-Lys-Ser-Ala-Ile-Lys-NH2
Molecular Formula C99H180N30O30S
Sl Sequence Palmitoyl-RSSAMDENSEKKRKSAIK-NH2
Solubility Soluble in DMSO
Appearance Freeze dried solid
Storage Store dry, frozen and in the dark
References Sevigny et al (2011)  Interdicting protease-activated receptor-2-driven inflammation with cell-penetrating pepducins. Proc Natl Acad Sci U S A 108(20) 8491 PMID: 21536878Michael et al (2013) Pharmacological inhibition of PAR2 with the pepducin P2pal-18S protects mice against acute experimental biliary pancreatitis. Am J Physiol Gastrointest Liver Physiol. 304(5) G516 PMID: 23275617Eftekhari et al (2024)Blockade of Proteinase-Activated Receptor 2 (PAR2) Attenuates Neuroinflammation in Experimental Autoimmune Encephalomyelitis. J Pharmacol Exp Ther. 388(1) 12 PMID: 37699708
Related areas All cell penetrating peptides >All protease activated receptor modulators >All immunology research categories >
Note The product is for research use only
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