Product Description
| Cat Number | PS-040 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | Fret substrate for MMP-3 and MMP-10 |
| Modification | 7-methoxycoumarin (Mca) at the N terminal, X is norvaline, Lysine 10 is substuted with a 2,4-dinitrophenyl (Dnp) group, and the C terminal is amidated |
| Purity | >95% by HPLC |
| Biomarker Target | Matrix metalloproteases |
| Sequence Three Letter Code | Mca-Arg-Pro-Lys-Pro-Val-Glu-Nval-Trp-Arg-Lys(Dnp)-NH2 |
| Molecular Formula | C78H110N22O20 |
| Sl Sequence | Mca-RPKPVEXWRK(Dnp)-NH2 |
| Solubility | Soluble in DMSO |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| References |
Gocheva et al (2006) Distinct roles for cysteine cathepsin genes in multistage tumorigenesis. Genes Dev. 20(5) 543 PMID: 16481467Aly et al (2009) Mycobacteria-induced granuloma necrosis depends on IRF-1. J Cell Mol Med. 13(8B) 2069 PMID: 18705699Bertran et al (2020) Design and synthesis of selective and blood-brain barrier-permeable hydroxamate-based gelatinase inhibitors. Bioorg. Chem. 94 103365 PMID: 31676116 Related areas_x000D_ All matrix metalloproteases modulators >All fluorescent labelled peptides >All substrate peptides > |
| Note | The product is for research use only |
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