Product Description
| Cat Number | PS-050 |
|---|---|
| Category | Peptide |
| Pack Size | 1 mg |
| Description | FRET substrate for endothelin-converting enzyme-1 (ECE-1) |
| Modification | 7-methoxycoumarin (Mca) at the N terminal, Lysine 9 has 2,4-dinitrophenyl (Dnp) attached |
| Purity | >95% by HPLC |
| Biomarker Target | Endothelin converting enzyme 1 |
| Sequence Three Letter Code | Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys-(Dnp) |
| Molecular Formula | C66H81N15O19 |
| Sl Sequence | Mca-RPPGFSAFK(Dnp) |
| Solubility | Soluble in DMSO |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| References |
Johnson and Ahn (2000) Development of an internally quenched fluorescent substrate selective for endothelin-converting enzyme-1. Anal Biochem. 286(1) 112 PMID: 11038281Bruce et al (2008) Hydrogen bond residue positioning in the 599-611 loop of thimet oligopeptidase is required for substrate selection. FEBS J. 275(22) 5607 PMID: 18959747Nelson et al (2009) Reduction of β-Amyloid Levels by Novel Protein Kinase Cϵ Activators. J. Biol. Chem. 284 34514 PMID: 19850930 Related areas_x000D_ All endothelin converting enzyme 1 modulators >All fluorescent labelled peptides >All substrate peptides > |
| Note | The product is for research use only |
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