Product Description
| Cat Number | SPR-407C |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100 µg x2 |
| Description | Human Recombinant Gamma Synuclein Protein Monomers |
| Applications | WB | SDS-PAGE | In vivo assay | In vitro assay |
| Target | Gamma Synuclein |
| Molecular Weight | 13.33 kDa |
| Cellular Localization | Cytoskeleton | Centrosome | Spindle | Perinuclear Region |
| Purity | >95% |
| Research Area | Neuroscience | Neurodegeneration | Alzheimer's Disease | Tangles & Tau | Neuroscience | Neurodegeneration | Parkinson's Disease | Synuclein |
| Swiss Prot | O76070 |
| Scientific Background | Gamma synuclein is a neuronal protein found in peripheral and motor nerve systems. It has been implicated in the hippocampal axon pathology in Parkinson's Disease (1). A change in the expression of gamma synuclein has been observed in the retina of patients with Alzheimer's disease (2). Its expression in breast tumors is also a marker for tumor progression (3). |
| Expression System | E. coli |
| Accession Number | NP_003078.2 |
| Gene Id | 6623 |
| Protein Length | Full length |
| Purification | Ion-exchange Purified |
| Storage | -80ºC |
| References | 1. Nishioka K., et al. (2010) Arch Neurol. 67(8): 970-975. 2. Surgucheva I., Newell K.L., Burns J., Surguchov A. (2014) Acta Neuropathol Commun. 2: 132. 3. Bruening. W., et al. (2000) Cancer. 88(9): 2154-2163. 4. Mukaetova-Ladinska E.B., et al. (2008) Dement Geriatr Cogn Disord. 26(1): 32-42. |
| Product Url | View Document |
| Note | The product is for research use only |
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