Food Safety Kits Available at Biotechnolabs
Kinase is the name given to an enzyme that catalyzes the transfer of a phosphate group from ATP to another molecule. There are over 518 kinases encoded by the human genome including both protein and lipid kinases and it has been estimated that kinases regulate approximately 50% of the cellular functions and because of these kinases have become the targets of interest in the treatment of various types of diseases.
Approximately 10% among these kinases are pseudokinases as they lack the main residues required for the catalytic activity. They all have a binding site for substrate protein, Mg2+- ATP (Phosphate donor) and various regulatory sites. The process of phosphorylation is temporary as the proteins phosphorylated get dephosphorylated to the previous form of protein. Phosphorylation may bring conformational changes, affect enzymatic activity, stability or degradation, association with other proteins and localization within the cell. Kinases are involved in various cellular functions like metabolism, regulation of cell cycle, cell adhesion, migration, cellular differentiation and survival. Hence Biotechno Labs are here to provide Kinase related products to the scientific community.
