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PI4-Kinase (PI4Ks)

By: Team BTL Biotechno Labs Pvt. Ltd.

PI4-kinase, or phosphatidylinositol 4-kinase (PI4K), is an enzyme involved in the synthesis of phosphatidylinositol 4-phosphate (PI4P), a crucial lipid signaling molecule in cells. PI4P is a precursor for phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) and therefore is involved in the regulation of membrane trafficking, including the transport of vesicles containing proteins and lipids within the cell. Membrane trafficking is crucial for maintaining cell structure, communication, and various other functions.

PI4Ks consist of four isozymes in two subfamilies: type II kinases (PI4KIIα and PI4KIIβ) and type III kinases (PI4Kα and PI4Kβ). The structure of type II and III kinases differs significantly, which informs both their function and potential interactions with other proteins. As a result, the two types exhibit distinct modes of stimulation and inhibition.

Echelon Bioscience is a global leader in biochemical reagents, assays, lipids, and peptides, catering to both academic research and pharmaceutical development. As an authorized distributor of Echelon Bioscience in India, BTL Biotechno Labs Pvt. Ltd. takes pride in offering their comprehensive range of PI4-kinase to the scientific community, enhancing the understanding of its role in cell signaling and trafficking at competitive prices.

PI4-Kinase Activity Assay, Cat# K-4000K; PI4-Kinase beta (PI4Kb), active, Cat# P32-102G; PI(4)P Mass ELISA Kit, K-4000E; PI4-Kinase II alpha (PI4KIIa), active, Cat# P21-10G; PI4-Kinase II beta (PI4KIIb), active, Cat # P22-10G