Human 2B4/CD244/SLAMF4 Protein (2B4-HM201)
SKU: BTL-KB-P-00003 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | 2B4-HM201 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human 2B4/CD244/SLAMF4 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Cys22-Arg221. |
| Target | 2B4/CD244/SLAMF4 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | 2B4 (CD244) is expressed by memory-phenotype CD8(+) T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 is conserved in humans and mice, and a number of reports have linked 2B4 with activation of lymphocytes.Engagement of 2B4 on NK cell surfaces with specific antibodies or CD48 can trigger cell mediated cytotoxicity, interferon γ secretion, phosphoinositol turnover and NK cell invasiveness. |
| Molecular Mass | The protein has a predicted MW of 49 kDa. Due to glycosylation, the protein migrates to 68-75 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Cys22-Arg221 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per ug by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q9BZW8-2 |
| Amino Acid Sequence | Recombinant Human 2B4/CD244/SLAMF4 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Cys22-Arg221. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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