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Human TPBG/5T4 Protein (5T4-HM201)

SKU: BTL-KB-P-00006 | Host: Human | Brand: Kactus Bio
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Product Description

Cat Number 5T4-HM201
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Human TPBG/5T4 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ser32-Ser355.
Target TPBG/5T4
Host Human
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Scientific Background The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR4/CXCL12, Wnt, and Hippo pathways which may all contribute through the mobilization of CSCs.
Molecular Mass The protein has a predicted MW of 62.08 kDa. Due to glycosylation, the protein migrates to 75-105 kDa based on Bis-Tris PAGE result.
Sl Sequence Ser32-Ser355
Solubility Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Appearance Lyophilized
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System HEK293
Gene Id Q13641
Amino Acid Sequence Recombinant Human TPBG/5T4 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ser32-Ser355.
Storage -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Pdf View Document
Note The product is for research use only
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