Product Description
| Cat Number | 66263-2 |
|---|---|
| Category | Biochemical |
| Pack Size | 5g |
| Description | Melatonin is a hormone responsible for mediating photoperiodicity in mammals. It inhibits cerebellar nitric oxide synthetase, and is a peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. It inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action. Melatonin is characterized with variety of properties such as antioxidant, autocoid, paracoid and hormonal properties, as well as anti- inflammatory and anti-apoptotic properties. Melatonin is implicated in the regulation of seasonal reproduction, energy metabolism and thermoregulation in mammals. Melatonin also plays a vital role in the lessening of neonatal hypoxia–ischemia (HI) induced endoplasmic reticulum (ER) stress and conserves sirtuin 1( SIRT-1) expression. |
| Research Field | Biochemicals/Chemicals |
| Note | The product is for research use only |
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