Biotinylated Human/Mouse/Rat Activin A Protein (ACV-HM401B)
SKU: BTL-KB-P-00030 |
Host: Human/Mouse/Rat |
Brand: Kactus Bio
Product Description
| Cat Number | ACV-HM401B |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Biotinylated Human/Mouse/Rat Activin A Protein is expressed from HEK293 with Avi tag at the C-terminus. It contains Gly311-Ser426. |
| Target | Activin A |
| Host | Human/Mouse/Rat |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Scientific Background | Activin-A, a member of the TGF-β superfamily, Extensive research over the past decades illuminated fundamental roles for activin-A in essential biologic processes, including embryonic development, stem cell maintenance and differentiation, haematopoiesis, cell proliferation and tissue fibrosis. Activin-A signals through two type I and two type II receptors which, upon ligand binding, activate their kinase activity, phosphorylate the SMAD2 and 3 intracellular signaling mediators that form a complex with SMAD4, translocate to the nucleus and activate or silence gene expression. |
| Molecular Mass | The protein has a predicted MW of 14.78 kDa. Due to glycosylation, the protein migrates to 15-18 kDa under reduced (R) condition, and 23-30 kDa under Non reduced (N) condition based on Bis-Tris PAGE result. |
| Sl Sequence | Gly311-Ser426 |
| Appearance | Liquid |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P08476 |
| Amino Acid Sequence | Recombinant Biotinylated Human/Mouse/Rat Activin A Protein is expressed from HEK293 with Avi tag at the C-terminus. It contains Gly311-Ser426. |
| Storage | Valid for 12 months from date of receipt when stored at -80°C; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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